Cardiovascular Injections

Dobutamine Hydrochloride Injection

Approx Price: Rs 1 / Pack 
It is a derivative of dopamine with prominent beta one receptor activity and negligible chronotropic and peripheral vascular activity.
Composition : 250mg/5 ml
Indications : Refractory chronic congestive heart failure not responding to digoxin. For inotropic support in bacteremic shock.
Contraindications : Acute myocardial infarction.
Safety Profile : Thrombocytopenia, platelet dysfunction, uncontrolled hypertension, diabetic retinopathy, and pregnancy
Adverse Effects : Increase in HR, BP.
Drug Interactions : Nitroprusside.
Dosage :2.5 to 10 mcg/kg in 5% dextrose by slow iv infusion.
Purity :Not less than 99%.

Verapamil Injection

Approx Price: Rs 1 / Pack 

It has potent antiarrhythmic activity more so in supraventricular arrhythmias because of its potent calcium channel blocking property. Same activity is responsible for its antianginal and antiischemic action.

Composition :5mg/ 2ml
Indications :PSVT, atrial flutter/fibrillation with tachyarrhythmias and pre mature beats. Angina pectoris, chronic coronary insufficiency, variant angina, hypertension.
Contraindications :Acute M.I., cardiovascular shock, severe AV block and sick sinus syndrome.
Safety Profile :Ability to do skilled job may be impaired, hepatic & renal impairment.
Adverse Effects :Constipation, nausea, vertigo, dizziness, headache, flushing, faigue, ankle oedema, erythromelalia and paraesthesia.
Drug Interactions :Antihypertensives including beta blockers, neuromuscular blockers, digitalis and carbamazepine actions repotentiated. Use with quinidine may cause cardiac depression.
Dosage :Adults - 40-80 mg 2-3 times daily orally. i.v. dose 5mg slowly, repeat further 5mg if needed, children - upto 6 yrs. 40-80mg twice a day, 6-12 yrs - 40-120mg twice a day.

Nimodipine Injection

Approx Price: Rs 1 / Pack 
It is a calcium channel blocker. It enters the brain and it acts by blocking the entry of extracellular calcium in neurones. Being highly lipophilic nimodipine has greater action on the cerebral vessels.
Composition : 30mg/50ml
Indications : Subarachnoid haemorrhage, ischaemic neurological deficits senile dementia.
Safety Profile : Patients with hypotension, patients with impaired renal and hepatic functions, patients with cerebral oedema, patients with raised intra cranial pressure, monitor pulse and BP during IV therapy.
Adverse Effects : Epigastric distress, fall in blood pressure, flushing, nausea.
Purity :Not less than 99%.
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