Send SMS
Contact Us

Cardiovascular Injections

Dobutamine Hydrochloride Injection

Dobutamine Hydrochloride Injection

It is a derivative of dopamine with prominent beta one receptor activity and negligible chronotropic and peripheral vascular activity.
Composition : 250mg/5 ml
Indications : Refractory chronic congestive heart failure not responding to digoxin. For inotropic support in bacteremic shock.
Contraindications : Acute myocardial infarction.
Safety Profile : Thrombocytopenia, platelet dysfunction, uncontrolled hypertension, diabetic retinopathy, and pregnancy
Adverse Effects : Increase in HR, BP.
Drug Interactions : Nitroprusside.
Dosage :2.5 to 10 mcg/kg in 5% dextrose by slow iv infusion.
Purity :Not less than 99%.

Verapamil Injection

Verapamil Injection

It has potent antiarrhythmic activity more so in supraventricular arrhythmias because of its potent calcium channel blocking property. Same activity is responsible for its antianginal and antiischemic action.

Composition :5mg/ 2ml
Indications :PSVT, atrial flutter/fibrillation with tachyarrhythmias and pre mature beats. Angina pectoris, chronic coronary insufficiency, variant angina, hypertension.
Contraindications :Acute M.I., cardiovascular shock, severe AV block and sick sinus syndrome.
Safety Profile :Ability to do skilled job may be impaired, hepatic & renal impairment.
Adverse Effects :Constipation, nausea, vertigo, dizziness, headache, flushing, faigue, ankle oedema, erythromelalia and paraesthesia.
Drug Interactions :Antihypertensives including beta blockers, neuromuscular blockers, digitalis and carbamazepine actions repotentiated. Use with quinidine may cause cardiac depression.
Dosage :Adults - 40-80 mg 2-3 times daily orally. i.v. dose 5mg slowly, repeat further 5mg if needed, children - upto 6 yrs. 40-80mg twice a day, 6-12 yrs - 40-120mg twice a day.

Etoposide Injection

Etoposide Injection

Amphotericin-B Injection

Amphotericin-B Injection
Composition : 50mg, 100mg
Indication :Topically for oral, vaginal and cutaneous candidiasis and otomycosis. Most effective for various types of systemic mycoses. Intravenously for treatment of progressive and potential fatal fungal infections. Intestinal moniliasis.
Dosage :Orally-50-100mg four times.For Systemic mycoses, Initially 1 mg test dose is injected over 20 mins i.v. followed by 0.3 mg/kg body wt is infused over 4-8hrs. Max of 0.7 mg/kg body wt
Contra-Indications :Renal impairment, epilepsy.
Special Precautions :Test dose is must before giving intravenously. Adverse reactions can decrease with inclusion of hydrocortisone 0.6 mg/kg body wt in the Infusion
Paediatrics :Reduced dose may be necessary.
Pregnancy :No evidence of risk.
Lactation :No evidence of risk.
Elderly Safe :
Side–effects :Chills, fever, aches, nausea, vomiting and dyspnoea. Thromboflebitis of the injected vein. (azotemia, reduced g.f.r, acidosis, hypokalemia and inability to concentrate urine). Anaemia due to bon marrow depression. C.N.S. toxicity.
Drug interactions :Potentiation of potassium loss by corticosteroids, increases digital toxicity, causes hypokalemia with diuretics, antagonism with ketoconazole, aminoglycosides enhance renal toxicity, induce toxicity enhanced in presence of other nephrotoxic agents.

Leuprolide Injection

Leuprolide Injection

Composition- : Each 0.5ml Contains : Leuprolide Acetate 1mg
Leuprolide acts as an agonist at pituitary GnRH receptors. By interrupting the normal pulsatile stimulation and the desensitization of the GnRH receptors; it indirectly down regulates the secretion of gonadotropins luteinizing hormone (LH) and follicle-stimulating hormone (FSH) leading to hypogonadism,  thus a dramatic reduction in estradiol .

Specification-pH range – : 5.5 to 6.5
Leuprolide acetate is a synthetic nonapeptide analog of naturally occurring gonadotropin releasing hormone (GnRH or LH-RH). The analog possesses greater potency than the natural hormone. It is a sterile, aqueous solution intended for subcutaneous injection.
Indication :Advanced prostatic carcinoma when orchidectomy or oestrogen administration is not indicated.
Dosage :-SC inj., 1 mg single dose.
Contraindications:-Pregnancy, in women who may become pregnant while receiving the drug, and during lactation. Sensitivity to benzyl alcohol (found in leuprolide injection). Undiagnosed abnormal vaginal bleeding. Hypersensitivity to GnRH or GnRH agonist analogs. The 30-mg depot in women.
Precautions:-Patients with metastatic vertebral lesions and/or with urinary tract obstruction should be closely observed during the first few weeks of therapy. Patients with known allergies to benzyl alcohol, an ingredient of the drug's vehicle, may present symptoms of hypersensitivity, usually local, in the form of erythema and induration at the injection site.
Drug interaction:Administration of leuprolide acetate in therapeutic doses results in suppression of the pituitary-gonadal system. Normal function is usually restored within 4 to 12 weeks after treatment is discontinued. Administration of leuprolide acetate in therapeutic doses results in suppression of the pituitary-gonadal system. Normal function is usually restored within 4 to 12 weeks after treatment is discontinued.
Adverse Effect-:High blood pressure, ischemia, insomnia, constipation, urinating more often than usual, bone pain, loss of movement in any part of your body; swelling, rapid weight gain.
Storage:: Store unopened bottles in the refrigerator. Vials can be kept at room temperature (less than 86 degrees F or 30 degrees C). Do not freeze. Protect from light.

Dacarbazine Injection

Dacarbazine Injection

Each lyophilized vial contains:- Dacarbazine USP 100mg/ 200 mg/ 500mg
It is an unidarole derivative. Exact machanism of action is not known. Three hypothesis have been proposed.
• Inhibition of DNA synthesis by acting as purine analogue.
• Action as an alkylating agent.
• Interaction with - SH group. pH ranges from 3.0 to 4

Indication :Dacarbazine for injection is indicated in the treatment of metastatic malignant melanoma. In addition, dacarbazine for injection is also indicated for Hodgkin's disease as a secondary-line therapy when used in combination with other effective agents.
Dosage :-Malignant melanoma : 2-4.5 mg/kg/day for 10 days may be repeated at 4 weeks intervel or 250 mg/ml of body surface area (BSA)/day for 5 days repeated after 3 weeks.
Contra Indications:-Dacarbazine for injection is contraindicated in patients who have demonstrated a hypersensitivity to it in the past.
Precautions:-Breast-feeding is usually stopped while using anticancer drugs. Dacarbazine should be used only when clearly needed during pregnancy.
Drug interaction:Impairs immune response to vaccines; possible infection after admin of live vaccines. Effect increased by CYP1A2 inhibitors e.g. amiodarone, ciprofloxacin, fluvoxamine, ketoconazole, lomefloxacin, ofloxacin and . Effect decreased by CYP1A2 inducers e.g. aminoglutethimide, carbamazepine, and rifampicin.
Adverse effects:Haemopoietic depression invading mainly leucocytes and platelets anaphylactoid reaction, anorexia, nausea, vomiting, diarrhoea, influneza like syndrome, alopecia, facial flushing, paresthesia, ash liver function and renal function abnormalities
Storage:Store in a refrigerator 2°C to 8°C (36°F to 46°F). dacarbazine Use within 8 hours of reconstitution. Protect from light

Dexamethasone Injection

Dexamethasone Injection

Amikacin Injection

Amikacin Injection
Composition :100mg/2ml, 250 mg/2ml & 500mg/2ml
Amikacin:It is semisynthetic aminoglycoside virtually identical to its parent compound kanamycin. Amikacin is effective against a variety of aerobic gram-negative bacilli including those that are resistant to gentamicin and other Aminoglycosides (Escherichia Coli, Pseudomonas Aeruginosa, Indole positive and negative Proteus species Klebsiella, Enterobacter, Serratia, Acinetobacter, Citobacter Freundii and providencia stuarti). It is effective against both penicillinase and non-penicillinase producing Staphylococcus Aureus. Amikacin shows excellent activity against Mycobacterium Tuberculosis and Atypical Mycobacteria.
Indications :Bacteraemias, septicaemias, respiratory tract, bone and joints, CNS (including meningitis), soft tissue, intra-abdominal infections (including peritonitis), burns and post-operative infections.
Dosage :IM route for Adults, Children: 15 mg/kg body weight/day in 2 or 3 divided doses. Max of 1.5 gm/day. Neonatals: 10 mg/kg body weight followed by 7.5 mg/kg every 12 hours IV route dosage is identical, injection spread over 2-3 mins or a slow IV infusion spread over a period of 30-60 mins and for infants and neonatals 1-2 hours.
Contra-Indications:Known hypersensitive to aminoglycoside.
Special Precautions:Impaired renal function, ensure adequate hydration.
Paediatrics :Use with caution.
Pregnancy:Contra-indicated
Lactation:Contra-indicated
Elderly :Use with caution.
Side-Effects:Contra-indicated
Elderly :Ototoxicity, Nephrotoxicity, Neuromuscular Blockade, Skin rash, Tremors, Eosinophlia, Nausea, Vomiting.
Purity :Not less than 99%.

Diclofenac Sodium Injection

Diclofenac Sodium Injection
Composition :75mg/3ml, 750mg/30ml
Dosage :60 mg b.i.d./ t.i.d IM - 75 mg 1-2 times / day
Purity :Not less than 99%.

Piracetam Injection

Piracetam Injection
Composition : 200mg/ 15ml (60ml pack)
Indications :Mental retardation, Learning problems in children, behavioural problem and confusion state in elderly patients, cerebro-vascular accidents, cerebral insufficiencies.
Contraindication:Severe renal and hepatic impairment. Hypersensitivity.
Safety Profile :Drug should be withdrawn gradually, Patients with history of renal & hepatic diseases cardiac disorders.
Adverse Effects :Insomnia, nervousness, increased motor activity, depression, weight gain, diarrhoea, skin rashes, epigastric distress, CNS stimulation. GI obstruction or perforation epilepsy, phaeochromocytoma, extra pyramidal symptoms.
Drug Interactions :Thyroid hormones, inhibits and severe sickling of RBC's. Oral anticoagulants : Increased prothrombin time.
Dosage :Adults : 800mg t.i.d. Children 50mg/kg body weight in 3 separate doses. Reduce the initial dose by half after obtaining desired result.
Purity :Not less than 99%.

Docetaxel Injection

Docetaxel Injection


Composition :20mg/0.5 ml, 80mg/2ml, & 120mg/3ml
Indication :Cancer : Breast, non-small cell lung cancer, prostate, bladder, stomach, Esophagus, overy,head and neck.
Dosage :-Administered parenterally. The dose should be individualized depending on the size of the patient and whether or not other medicines are also being taken. Adults: 60 to 100 mg /1.73 ml intravenously.
Contra Indications :-Hypersensitivity , alcohol abuse or history of, chickenpox, herps zoster, fluid in lungs, infection , liver disease.
Special Precautions :-Immunization specifically persons living in the patient’s household should not take oral polio vaccine.
Paediatrics :Only limited studies are done.
Pregnancy :-Contraindicated.
Lactation :-Generally not recommended.
Elderly :-Use with caution.
Side Effects :-Mild nausea and vomiting, headache, palpitation, tightness in chest, chest pain , heart problem , hypotension, or hypertension , congestion, diarrhoea, arthralgia, myalgia, puffiness of face, stomatitis , oedema, weight gain , tingling and numbness
Drug Interactions :-Amphotericin- B , ketoconazole , antithyroid agents ,erythromycin troleandomycin , colchicine, flucytosine, ganciclovir , zidovudine, interferon, cyclophosphamide, orphenadine, midazolam, radiation, therapy.
Indication :Malignant lymphoma. Gastro-intestinal tract carcinoma. Bronchogenic, bladder, breast & ovarian carcinoma. Wilms tumour. Acute myeloblastic leukaemia
Dosage :-1.2-2.4 mg/kg body wt or 60-75 mg/sq metre of body surface given as a single dose every 3 week by slow i.v. inj.
Contra Indications :-Cardiac disease. Hepatic dysfunction.
Special Precautions :-ECG changes, arrhythmias, hypotension, or be delayed congestive heart failure.
Paediatrics :Reduced dose necessary.
Pregnancy :-Not usually prescribed.
Lactation :-Not prescribed.
Elderly :-Reduced dose may be necessary.
Side Effects :-Cardiotoxicity, alopecia, Bone marrow depression, alopecia, cardiomyopathy, stomatitis, vomiting and local tissue damage.
Drug Interactions :-Cyclosporin, cardiotoxic agents potentiates the cardiotoxicity.
Purity :Not less than 99%.

Cefuroxime Injection

Cefuroxime Injection
Each vial contains :-
Cefuroxime - 500 mg and 1.0 gm
Quality Specification:
Chromatographic Purity - NLT 99.5%
Pack Size: vial

Composition :250mg,500mg,750mg,1 gm
CEFUROXIME: :-It is resistant to most beta lactamases and is active against a wide range of Gram-positive and Gram-negative organisms. The most important use of cefuroxime is in meningitis caused by H Influezae, Meningo Cocci and Pneumo Cocci because it attains high concentrations in CSF.
Indication :Respiratory tract, Genito-urinary tract, skin and soft tissue infections, gonorrhoea, acute gonococal urethritis and cervicitis meningitis, prophylaxis against infections in surgical procedures.
Dosage :-750 mg thrice daily i.m. or i.v.Severe infections : 1.5 gm thrice daily i.v. Total dose 3-6 gm daily
Infants and Children :-30-100 mg/kg body wt daily in 3-4 divided doses
Neonates :-30-100 mg/kg body wt in 2-3 divided doses.
Meningitis :200-240 mg/kg body wt i.v. daily in 3-4 divided doses.
Contra-Indications :-Patients with known hypersensitivity to cephalosporin antibiotics
Special Precautions :-Anaphylactic reaction to Pencilins, Pseudo Membranous Colitis
Paediatrics :-Not safe in children below 3 months
Pregnancy :-Use with caution
Lactation :-Use with caution
Side–effects :-Skin rashes, Eosinophillia and transient increase of Hepatic Enzymes
Drug Interactions :-Synergy with aminoglycosides
Purity :Not less than 99%.

Cefoperazone and Sulbactum Injection

Cefoperazone and Sulbactum Injection
Composition :0.5gm+0.5gm, 1gm+1gm

Cefotaxime and Sulbactam Injection

Cefotaxime and Sulbactam Injection

Composition : 500mg + 250mg, 1gm+0.5gm

Piroxicam Injection

Piroxicam Injection
Each vial contains :- Piroxicam….. 20mg/2ml
Quality Specification: Chromatographic Purity: NLT 99.5%
Pack Size: vial.

Piroxicam:Its anti- inflammatory potency is similar to indomethacin and analgesic action is greater than aspirin. It has useful antipyretic proerty.
Indications:Its anti- inflammatory potency is similar to indomethacin and analgesic action is greater than aspirin. It has useful antipyretic proerty.
Dosage:Rheumatod arthritis, osteroarthritis, ankylosing, Spondylitis: 20mg daily as single dose. Maint : 10-30 mg .Acute Musculo-skeletal disorders: 40mg in a single or divided doses for 7-14 days. Acute gout : 40 mg as a single dose. Maint : 40 mg in single or divided doses for 4-6 days.
Contra-Indications:Hypersensitivity , pregnancy children patients who develop asthama or allergy with other inflammatory drugs, lactation.
Special Precautions:Renal or hepatic dysfunction, asthma surgery, haemorrhagic disorders. Hypertension. Cardiovascular disease.
Paediatrics:Not recommended in age below 6 yrs.
Pregnancy:Contraindicated may affect the foetus.
Lactation:Safety not established.
Elderly:Reduced dose necessary.
Side Effects:Heart burn, nausea, anorexia, rashes, pruritus, C.N.S. manifestations. Oedema.
Drug Interactions:Potentiate anticoagulants. Diuretics increase risk of renal damage. Monitor lithium levels. Aspirin reduces serum levels.

Piracetam Injection

Piracetam Injection
Composition :200mg/ 15ml (60ml pack)
Indications :Mental retardation, Learning problems in children, behavioural problem and confusion state in elderly patients, cerebro-vascular accidents, cerebral insufficiencies.
Contraindications :Severe renal and hepatic impairment. Hypersensitivity.
Safety Profile :Drug should be withdrawn gradually, Patients with history of renal & hepatic diseases cardiac disorders.
Adverse Effects :Insomnia, nervousness, increased motor activity, depression, weight gain, diarrhoea, skin rashes, epigastric distress, CNS stimulation. GI obstruction or perforation epilepsy, phaeochromocytoma, extra pyramidal symptoms.
Drug Interactionsthyroid hormones, inhibits and severe sickling of RBC's. Oral anticoagulants : Increased prothrombin time.
Dosage :Adults : 800mg t.i.d. Children 50mg/kg body weight in 3 separate doses. Reduce the initial dose by half after obtaining desired result.
X
Provide Us More Details
Is this Requirement:

One Time Regular

How soon do you want this:

Immediate After 1 month

Purpose of Requirement:

Reselling End Use Raw Material

X

Looking for Cardiovascular Injections ?

country-ico

We will contact you soon !

Gaurav Chawla

(Director)

Health Biotech Limited

Chandigarh - 160022, India

More Categories

View All Categories »
Send SMS
Contact Us